QWO - A Brand New Treatment for Cellulite

Before and after QWO for cellulite

What is Qwo®?

Qwo® is a unique injectable that treats cellulite dimples.  It is the first and only FDA-approved treatment for moderate to severe cellulite dimpling.  Although the approval is specific for buttock dimples in adult women, studies continue for use in thigh dimples, which are currently considered "off-label".

Cellulite - a tough problem

Nearly half of all women are bothered by cellulite, and current treatments are either invasive and costly or superficial and temporary.  I have used Cellulaze for several years and have been pleased by its results but it is invasive, costly, and the effects take months to see.  We have been waiting for a better solution, and now we have it.

Just what is cellulite?

Cellulite is the dimply texture that typically occurs on women's thighs or buttocks.  It occurs from underlying fibrous tethering of connective tissue to the undersurface of the skin, thinning of the dermis itself, and bulging of the fat between the fibrous connective tissue.  Cellulite can occur even in young, fit women.  It seems genetically pre-determined rather than a result of weight gain or unhealthy life choices.

How hoes Qwo® work?

Qwo® is made from collagenase enzymes derived from a bacterium called clostridium histolyticum.  These enzymes likely help rearrange the fat cells and free the skin by releasing the fibrous bands that course through the fat and tether up to the skin.

Who is a good candidate for Qwo®?

It is important to distinguish between cellulite dimples and skin laxity, which can make similar contour irregularities.  Qwo® does not treat loose skin.  Dimples at a young age are almost certainly cellulite, whereas irregularities that smooth out with gentle lifting are likely skin laxity rather than cellulite dimpling.  Laxity tends to be more linear, while cellulite dimples tend to be more round.  These differences can be subtle, and there can be both laxity and cellulite in the same person.  In general, better results will be seen in patients who are younger and not obese.  For more widespread cellulite without significant dimpling, other treatments like Cellulaze may be indicated.

How is the procedure done?

The patient is photographed standing up, wearing thong-type photo panties and the injector will go over the photos with the patient to choose which dimples to inject.  These will be marked and another set of photos taken.  The injections are then done in a prone position.  A small amount of Qwo® is injected into each cellulite dimple through a tiny needle (the same as we use for Botox).  The injection procedure only takes a few minutes - the photos and marking take more time than the injections!

What to expect after the injection

The injections are done as a series of three sessions, with three weeks scheduled between each injection sesssion.  Most people will have some significant bruising. This is entirely normal, but will take time to resolve just like any bruise.  Pain is usually minimal.  Improvement or resolution of some dimples may be seen before the second or third session, and other less severe dimples may be treated at those sessions.

For more information

Visit QWO.com for much more detailed information including safety information and results of the clinical studies.

Douglas J. Mackenzie, MD

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